Anti-babesial Quassinoids from the Fruits of Brucea Javanica
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چکیده
منابع مشابه
Chemical Composition and Cytotoxic Activities of Petroleum Ether Fruit Extract of Fruits of Brucea javanica (Simarubaceae)
Purpose: To investigate the chemical composition and antitumor activity of the petroleum ether extract of the dried ripe fruits of Brucea javanica. Methods: The composition of petroleum ether extract was analyzed by gas chromatography/mass spectrometric (GC/MS) and their antitumor activities were determined by MTT assay. Results: GC/MS spectrometry results indicate that the petroleum ether extr...
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The leaf, root, and stem extracts of Brucea javanica were screened for phytochemical properties and antimalarial activity, after extractions with various organic solvents. Qualitative analysis of the phytochemical constituents showed the presence of the following secondary metabolites: terpenoids, saponins, flavonoids, steroids, phenols, glycosides, alkaloids, and anthraquinones. The extracts s...
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The purpose of this study was to develop a docetaxel microemulsion containing an anti-tumor synergistic ingredient (Brucea javanica oil) and to investigate the characteristics of the microemulsion. Brucea javanica oil contains oleic acid and linoleic acids that have been shown by animal and human studies to inhibit tumor formation. The microemulsion containing Brucea javanica oil, medium-chain ...
متن کاملChemical components, pharmacological properties, and nanoparticulate delivery systems of Brucea javanica
Brucea javanica has demonstrated a variety of antitumoral, antimalarial, and anti- inflammatory properties. As a Chinese herbal medicine, Brucea javanica is mainly used in the treatment of lung and gastrointestinal cancers. Pharmacological research has identified the main antitumor components are tetracyclic triterpene quassinoids. However, most of these active components have poor water solubi...
متن کاملEvaluation of Antidiabetic and Antioxidant Properties of Brucea javanica Seed
The ethanol extract of B. javanica seed was fractionated with solvents of different polarities and tested for antioxidant activities by several assays including DPPH radical scavenging activity, ferric reducing antioxidant power (FRAP), ferrous ion chelating activity (FCA), and nitric oxide radical scavenging activity (NORSA) along with their polyphenolic contents. Antidiabetic activity was eva...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2008
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x0800300207